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Introduction Inflammatory bowel disease (IBD) refers to chronic inflammatory disorders of the gastrointestinal (GI) tract, primarily consisting of two subtypes: ulcerative colitis (UC) and Crohn's disease (CD)

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As proof, ASCT2 ( SLC1A5 ) knockdown in osteosarcoma and cervical cancer cells can induce upregulation of SNAT1 ( SLC38A1 ) (Broer et al., Glutamine catabolism, namely glutaminolysis, begins with its conversion to glutamate, which is catalyzed by the glutaminase (GLS) (Hassanein et al., 2013

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